3000 Center Green Drive Ste. #210, Boulder, CO 80301

​1127 Pennsylvania St., Denver, CO 80203

ph: (720) 273-3568 | fax: (720) 612-4271

Imagine having the ability to take hormones safely! Appropriate use of bioidentical hormones—plant chemicals extracted from soy and yams that are identical in molecular structure to hormones women make in their bodies—gives you all the benefits of hormone replacement therapy while minimizing risk. 

A 2002 Women’s Health Initiative study on hormone replacement therapy revealed that use of synthetic estrogen and progestin found in Premarin and Provera increases risk of breast cancer and cardiovascular disease and causes other significant side effects. Unfortunately, these and other synthetic hormones remain on the market and are still being prescribed.

Hormones must be balanced like a symphony to prevent dysfunction and disease. Low levels of estrogen, progesterone, and testosterone can cause PMS, hot flashes, vaginal dryness and atrophy, and decreased sexual desire and satisfaction. Hormone replacement therapy is necessary for many women, including those with early-onset menopause and those who have had hysterectomies, and studies have found bioidentical hormones to be safe and life-enhancing.

At Holos Health, we utilize bioidentical hormones and appropriate testing to minimize your risk of developing the hormone deficiency symptoms listed above as well as breast cancer (and other types of cancer), heart attacks and strokes, osteoporosis, senile dementia, and autoimmune disorders.

Estrogen

Thanks to Functional Medicine and current research, we now know that the metabolic pathway in which estrogen is broken down can have a profound effect on breast tissue and women’s risk of developing breast cancer. Through a simple urine test, we can now determine the metabolic pathway for estrogen metabolism in your body and help you significantly decrease your risk of developing breast cancer, heart disease, senile dementia, osteoporosis, and sexual dysfunction as well as many chronic and debilitating diseases.

Our bodies produce three main forms of estrogen that can be replaced with bioidentical hormones. We often recommend a combination of E2 and E3 compounded in a cream or gel.

  • Estrone (E1), which dominates after menopause, is produced in fat cells and post-menopausal ovaries and adrenals. The synthetic form has been implicated in increasing breast cancer risk.
  • Estradiol (E2), the most powerful form, is produced mainly in premenopausal ovaries. E2 is the main form of estrogen responsible for healthy bones. Synthetic forms, when taken orally, can increase risk of cardiovascular disease. If not metabolized properly, they also increase breast cancer risk.
  • Estriol (E3), the weakest form, dominates during pregnancy. It does not increase breast cancer risk and, in some studies, has been shown to decrease the risk. When used intra-vaginally as a cream or gel, it can reduce vaginal dryness and help prevent vaginal atrophy and bladder issues.


Progesterone
Progesterone should always be taken in conjunction with estrogen. The difference between synthetic forms of progesterone (progestins) and the natural form (progesterone) is dramatic. As with estrogen, there is significant benefit to using a bioidentical form. We often recommend a bioidentical transdermal cream compounded specifically to your needs.  

Testosterone
Often referred to as "the hormone of desire," testosterone, along with estrogen and progesterone, can make a significant difference in maintaining optimal sexual function. Testosterone is the one hormone that can help reverse bone loss. With its anabolic (building) effect, it has been found to improve strength, stamina, and muscle mass. We often recommend compounded bioidentical testosterone customized to the patient’s needs in a cream or gel.  


Thyroid
Hypothyroidism is increasingly common as people age, and the hypothyroid condition Hashimoto's thyroiditis may be associated with gluten sensitivity and other autoimmune disorders. We help patients find relief from these conditions with dessicated thyroid extracts (DTE)—bioidentical hormones derived from pig thyroid tissue—a safe alternative to synthetic thyroid.

Adrenals
It all starts with the adrenals. Located above the kidneys, adrenals are the source of precursors to all your sex hormones. The adrenal glands produce cortisol, which can have a major effect on sugar metabolism and fat storage. Increased stress—nearly universal among modern humans—is the main cause of adrenal fatigue. DHEA, an anabolic (building) steroid also produced by the adrenal glands, declines significantly with age and sometimes needs to be supplemented with bioidentical hormones. 

Bioidentical Hormones